This autobiography relates Rush's experiences in college and medical school; his meetings with notable doctors; his life in Scotland, England, and France; his medical views; the military and politics during the Revolutionary War; and brief sketches of personalities of that period.

After emigrating from Germany to Philadelphia in 1796, Peter Adolph Grotjahn established himself within the city's mercantile community, trading opportunistically both inland and coastwise as far as the Caribbean. In 1812, he began publishing a commercial newspaper, Grotjan's Philadelphia Public Sale Reports and he became increasingly active in local Democratic Party politics. The APS copy of Peter Grotjahn's memoir is a typescript copy of an original volume held at the Historical Society of Pennsylvania. Written for his grandchildren, the memoir begins with a relatively brief genealogical discussion, but concentrates on his personal and political life and commercial experiences prior to 1817. The last section of the autobiography was completed posthumously from notes, and includes extracts from Grotjahn's diary as late as 1844.

These photostats are selections from the original manuscript, which is a portion of a volume entitled "Letters, facts, and observations upon a variety of subjects." The topics include medicine, slavery, the African church, gossip and social events, the deaths of prominent Philadelphians, and Rush's philosophy on various subjects. Contains questions for Alexander McGillivray, on diseases, mortality, passions of Creek Indians.